The following NPCs can be found in Blackrock Spire.
Questgivers
Neutral
- File:IconSmall DragonRed Small.gif Acride <Scarshield Legion>
- File:IconSmall EarthenSouth Small.gif Elder Stonefort
Bosses
- File:IconSmall SpawnBlack Small.gif General Drakkisath
- File:IconSmall Wolf Small.gif Gizrul the Slavener
- Goraluk Anvilcrack <Blackhand Legion Armorsmith>
- File:IconSmall DrakeChromatic Small.gif Gyth <Rend Blackhand's Mount>
- File:IconSmall Wolf Small.gif Halycon
- Highlord Omokk
- File:IconSmall Spider Small.gif Mother Smolderweb
- File:IconSmall SpawnBlack Small.gif Overlord Wyrmthalak
- File:IconSmall Fire Small.gif Pyroguard Emberseer
- Quartermaster Zigris <Bloodaxe Legion> (Marked as rare but is not)
- Shadow Hunter Vosh'gajin
- File:IconSmall SpawnBlack Small.gif Solakar Flamewreath (Summoned through [Father Flame] event)
- File:IconSmall CoreHound Small.gif The Beast
- Urok Doomhowl (Summoned using [Omokk's Head] on [Roughshod Pike] at Urok's Tribute Pile)
- War Master Voone
- File:IconSmall Rend Small.gif Warchief Rend Blackhand
Other Notable NPCs
Neutral
- File:IconSmall WhelpBlue Small.gif Awbee
- Bijou
- Finkle Einhorn (Appears upon skinning The Beast)
- File:IconSmall Trogg Small.gif Warosh <The Cursed>
Hostile
- Bannok Grimaxe <Firebrand Legion Champion> (Rare)
- File:IconSmall Felguard Small.gif Burning Felguard (Rare, summoned by Scarshield Warlock)
- File:IconSmall Spider Small.gif Crystal Fang (Rare)
- Ghok Bashguud <Bloodaxe Champion> (Rare)
- Jed Runewatcher <Blackhand Legion> (Rare)
- File:IconSmall Nefarian Small.gifFile:IconSmall Nefarius Small.gif Lord Victor Nefarius <Lord of Blackrock>
- Spirestone Battle Lord (Rare)
- Spirestone Butcher (Rare)
- File:IconSmall OgreMage Small.gif Spirestone Lord Magus (Rare)